Similac Sensitive vs Total Comfort: Which Baby Formula to Choose?

Last Updated: 03 February 2021
Similac Sensitive Vs Total Comfort

The digestive system of your baby is very sensitive and may be intolerant to certain products. Often moms think that milk is a universal food for children but that belief is very inaccurate.

You have to remember - each baby is unique, and has different reactions to a certain product. And milk allergy is not that uncommon, especially among babies. Your child may be lactose intolerant or allergic to certain kinds of ingredients. If you continue feeding him/her regular formula, it may cause severe problems. If your child experiences discomfort, it is time for you to consider changing the infant formula.

Similac is the most trusted brand when it comes to milk powder. Their two most popular variants are Total Comfort and Sensitive. They are best for babies with sensitive tummies and are extremely easy to digest. In this article, we are going to present to you a fair comparison - Similac Sensitive vs Total Comfort. And here, you will learn about which of these 2 are the very best option you can choose.

So without further ado, let’s take a look at the Similac Sensitive vs Total Comfort case.

Similac: a Brief Brand Review

The brand Similac was developed by Allen Bosworth, a famous milk chemist. Since then it is among the most trusted brands of infant formula all over the world. The credit goes to its natural ingredients and lack of any artificial growth hormones. And it’s important to note that according to a lot of baby formula reviews, Similac has put to rest most parents’ worries about the baby formulae and changed their mind about it overall. And that’s a good thing, since it’s about time we stop demonizing milk formulae.

Similac Sensitive Overview

Similac Sensitive Infant Formula with Iron
  • Similac is the first leading infant formula brand with no artificial growth hormone* (*no significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows)
  • Similac Sensitive Infant Formula is a milk-based formula for your baby's first year that is specially designed for fussiness and gas due to lactose sensitivity
  • NUTRIENTS: Features OptiGRO, our exclusive blend of DHA, Lutein and Vitamin E, special nutrients found in breast milk that are important for helping support baby's brain and eye development
  • TRUSTED FORMULA: Similac is the #1 brand chosen by moms§ (§Total US infant formula, all outlets as of 3/31/2018, Nielsen data)

This formula is designed for your baby’s first year. Many babies behave fussily in the first year of weaning due to milk sensitivity. This may lead to several health issues such as gastric problems and bloating. And Similac is considered the best formula for gassy babies and has a non-GMO certification which makes it absolutely safe for children’s consumption.

The proteins in the formula are partially broken which becomes easy for the child to digest. It also contains human milk oligosaccharides which perform as immune nourishing prebiotic for your little one. According to Similac Sensitive reviews, parents are impressed by this particular inclusion. We are aware of the importance of DHA and as long as you are siding with this one, you have nothing to worry about.


  • Corn syrup
  • Milk protein isolate
  • High Oleic Safflower oil
  • Sugar
  • Soy oil
  • Coconut oil
  • Galactooligosaccharides
  • Cohnii oil
  • M. alpine oil
  • Beta-carotene
  • Lutein
  • Lycopene
  • Calcium phosphate
  • Potassium chloride
  • Potassium citrate
  • Sodium citrate
  • Magnesium phosphate
  • Calcium carbonate

These are some of the major ingredients of the Similac Sensitive variant.

Pros and Cons

  • Best for babies with gassy stomach
  • HMOs make it similar to breast milk
  • Contains all vital nutrients
  • Non-GMO certification
  • Reasonable price
  • Some infants may find it difficult to digest
  • Not for babies who have galactosemia

Similac Total Comfort Overview

Similac Total Comfort Infant Formula with Iron
  • Similac Total Comfort Infant Formula provides complete nutrition for your baby's first year and is formulated to be gentle on tiny tummies with partially broken down protein for easy digestion, prebiotics for softer stools
  • NUTRIENTS: Features OptiGRO, our exclusive blend of DHA, Lutein and Vitamin E, special nutrients found in breast milk that are important for helping support baby's brain and eye development
  • QUANTITY: When mixed as directed, 1 SimplePac makes approximately 28 six fluid ounce bottles
  • Caution- Not for infants or children with galactosemia

Similac Total Comfort formula is the best for babies who have digestion problems. It has protein isolates that eliminate the need of breaking down complex proteins by the digestive system. It is a hypoallergenic formula containing non-GMO ingredients.

It’s also important to note that a lot of Similac Total Comfort reviews praise the formula for having nutrients like vitamin E, iron, and many more.


  • Corn maltodextrin
  • Whey protein hydrolysate
  • High Oleic safflower oil
  • Sugar
  • Soy oil
  • Coconut oil
  • Beta-carotene
  • Alpine oil
  • Cohnii oil
  • Calcium citrate
  • Potassium phosphate
  • Calcium phosphate
  • Ascorbic acid
  • Choline bitartrate
  • Vitamin A palmitate
  • Sodium citrate
  • Calcium hydroxide

These are some of the ingredients that go into making the Total Comfort formula.

Pros and Cons

  • Has all the vital nutrients
  • Has no artificial hormones
  • Gluten-free
  • Non-GMO ingredients
  • It is also available in liquid form
  • Helps in the development of your child’s brain and eyes
  • Works as a substitute for mother’s milk
  • Not for babies with galactosemia
  • A bit expensive

Similac Sensitive vs Total Comfort Comparison

Similac Sensitive vs Total Comfort Comparison

Let us now get into Similac Total comfort vs Sensitive review 2021. understanding the points of difference in Similac Sensitive vs Total Comfort for babies debate is essential for all parents.


When it comes to nutrients, Total Comfort wins the category fair and square. It is packed with all the vital nutrients that your child needs. It also has an impressively low sugar content which makes it easy for your baby to digest.

The Sensitive variant contains a great number of nutrients as well but has a high sugar content that can make it harsh for your baby’s belly. On the other hand, Similac is a brand every parent trusts. It has come up with hypoallergenic formulas that solve nursing problems of many parents around the world. So it’s safe to say that this is the best Similac formula for constipation.

Impact on Stomach

Impact on Stomach

There is a major difference between Similac Sensitive and Total Comfort when it comes to their basic formula. The former has protein isolates that can be tough on your child’s tummy as it contains both whey and casein. While the latter has whey protein isolates that work best for newborns and sensitive tummies.

Corn Syrup

Total Comfort has no trace of corn syrup as it is very low in sugar content. Similac Sensitive on the other hand has corn syrup as its major ingredient.

Corn syrup is the main source of HMOs which works in favor of this variant.

Special Case

Special Case

If your child suffers from the condition of Galactosemia – avoid any of these products, since they are not appropriate for your baby. Instead, look for a diet that will suit your kid.

Packaging Variants

Both the variants come in powder form but Total Sensitive also comes in liquid variety. Thus, when we talk about variance in the Similac Total Comfort vs Similac Sensitive debate, the former wins again.

Summarizing Key Differences

Similac Total Comfort Similac Sensitive
Great for babies who experience discomfort due to feeding issues Relieves gas pain in babies
For babies who find it difficult to digest regular milk proteins Good for babies who have lactose sensitivity

Final Word

From points of comparison, be it Similac Pro Sensitive vs Pro Total Comfort or Similac Sensitive vs Total Comfort, the Total comfort range wins hands down. Although the price range is a little higher, it comes with all the goodness you can expect. However, the ultimate choice is of course up to you. Remember that which one you should pick also depends on the sensitivity of your child’s tummy. So if your child has only gassy stomach problems, you can simply buy Sensitive but if you notice digestion problems and sensitivity to lactose, you should pick Total Comfort.

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